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Oncometabolites and the Heart
November 11, 2024 | RR Baliga, MD, MBA
PodKast: Oncometabolites and The Heart |Dr RR Baliga 'Got Knowledge Doc' PodKasts for Cardio-Oncologists
References
- Baliga RR, Young JB. Energizing Diastole Heart Fail Clin. 2008;4(1):ix‐xiii. Energizing Diastole
- Sulkowski, P.L., Oeck, S., Dow, J. et al. Oncometabolites suppress DNA repair by disrupting local chromatin signalling. Nature (2020).
- Tumour metabolites hinder DNA repair
- Krebs Cycle Nobel Lecture
- Ivosidenib and Cardiogenic Shock
- Oncometabolite d-2-hydroxyglutarate impairs α-ketoglutarate dehydrogenase and contractile function in rodent heart. Proc Natl Acad Sci U S A.
- D-2-hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice. Genes Dev.
- Changes in Citric Acid Cycle and Nucleoside Metabolism Are Associated with Anthracycline Cardiotoxicity in Patients with Breast Cancer. J Cardiovasc Transl Res.
- Krebs Cycle Primer Khan Academy
- Taegtmeyer H, et al Oncometabolic Tracks in the Heart. Circ Res. 2017
- Axes of Oncometabolism in the Heart